A professional actor since the age of nine, Jennifer Jason Leigh earned her Screen Actors Guild card at 16 and dropped out of high school to study at the Lee Strasberg Institute and star in seedy made-for-TV movies.

Throughout her career, she has made a name for herself portraying helpless, damaged, or mentally unsound characters, often performing at a higher level than the material. Also known for extensively researching her roles, Leigh dropped down to less than 90 pounds for one of her first features as an anorexic teenager in the TV-movie The Best Little Girl in the World. Never one to shy away from touchy subject matter, her breakthrough role came in 1982 as the naïve high school girl who gets an abortion in Fast Times at Ridgemont High.

Not limiting herself to dramas, Leigh appeared as an isolated computer programmer in David Cronenberg's thriller eXistenZ and as an over-the-top mom in the comedy Skipped Parts. Around that time, she also appeared on-stage in Broadway and off-Broadway plays, most notably as dancer Sally Bowles in Cabaret.

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